tech
December 16, 2025
OpenAI-backed biotech firm Chai Discovery raises $130M Series B at $1.3B valuation
Chai is building foundation models for drug discovery, specifically to predict interactions between molecules so they could be reprogramed for cures.

TL;DR
- Chai Discovery raised $130 million in Series B funding at a $1.3 billion valuation.
- The company's total funding now exceeds $225 million.
- The funding round was led by General Catalyst and Oak HC/FT, with participation from multiple other investors including OpenAI.
- Chai Discovery utilizes AI to accelerate drug development, focusing on predicting biochemical molecule interactions.
- The startup's goal is to create a "computer aided design suite" for molecules.
- Chai 2, their latest AI model, demonstrates improved success rates in designing custom antibodies from scratch.
- CEO Josh Meier, formerly of Facebook and OpenAI, co-founded Chai Discovery in 2024.
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