health
Do natural GLP-1s work?
Roula Khalaf, Editor of the FT, selects her favorite stories in this weekly newsletter.
TL;DR
- Natural supplements Elcella and Calocurb are being explored as alternatives to synthetic GLP-1 weight-loss injections.
- Elcella stimulates the release of 'fullness hormones' GLP-1 and PYY using a blend of oils.
- Calocurb, derived from hops-flower extract, has shown reductions in hunger, cravings, and calorie intake.
- Both supplements aim to boost the body's natural production of GLP-1, potentially aiding weight loss and transition from injectable drugs.
- Experts express caution regarding the translation of lab or animal study results to human outcomes, citing limited human trial data for supplements.
- Some experts suggest that a healthy diet with increased protein and fiber could naturally stimulate GLP-1 and support weight management.
- Potential side effects like digestive issues have been reported with some supplements.