health
Co-Scientist
Finding new treatments for liver fibrosis
TL;DR
- Liver fibrosis is a scarring process that can lead to cirrhosis, causing over 1.4 million deaths annually.
- Gary Peltz at Stanford is using Co-Scientist to identify drugs that can treat liver fibrosis.
- Co-Scientist proposed three drug candidates, two of which were effective in lab tests using human liver cells.
- The cancer drug vorinostat was a standout pick, blocking 91% of a damage response contributing to liver scarring.
- Peltz suggests drugs that reshape gene activity may be a new generation of anti-fibrotic treatments.